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There are different amount of pitchers in a 40-man roster, whether you have 25 pitchers (in both the starting rotation and the bullpen) or just have 10, in any game, you can use all of your pitchers. However, you can't use a pitcher once they are taken out of the game.

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14y ago
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Wiki User

11y ago

no they can not

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Wiki User

13y ago

Alot.

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Q: How many pitchers can be used in one MLB game?
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