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The gene for hemophilia is carried on the X chromosome. A male has one X and one Y. Since the trait is recessive it would be easier for a male to get a recssive allele, rather than a female get two recessive alleles.

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13y ago
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15y ago

Hemophilia is a sex linked genetic disorder where the defective gene is located on an X chromosome.

Women have two X chromosomes while men have one X chromosome and one Y chromosome.

Thus women have a spare X chromosome which 'backs up' for one which may carry the defect.

However if men inherit a faulty X chromosome from their mother, they will definitely get the disease and this is why the disorder is almost entirely manifested in males.

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Q: Why is hemophilia more common in the males than females?
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The genes associated with Hemophilia A and B are located on the X chromosome, which is one of the 2 sex chromosomes. For males, who have only 1 X chromosome, 1 altered copy of the gene in each cell is sufficient to cause hemophilia. In females, who have 2 X chromosomes, a mutation would have to occur in both copies of the gene to cause hemophilia. Since it is unlikely that females will have 2 altered copies of this gene it is therefor very rare for females to have hemophilia.


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