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It depends on the particular drug and what class of drug it belongs to. But for some of the most popular drugs it's generally the following;
- Amphetamines (psychological addiction, psychosis, irritability, fatigue, weight loss)
- Alcohol (physical and psychological addiction, brain damage, liver damage, cancer of the mouth, throat, esophagus and stomach, early onset alzheimers, parkinsons disease, korsakoff's syndrome, coma, death)
- Barbiturates (physical and psychological addiction, coma, death)
- Cannabis (clouded thinking, forgetfulness, when smoked along with tobacco reduced stamina, weight gain)
- Cocaine (psychological addiction, psychosis, anxiety, fatigue, weight loss, erosion of the nasal passages when snorted, lung problems when smoked)
- Ecstacy (psychological addiction, psychosis, depression, fatigue, weight loss)
- Ketamine (psychological addiction, psychosis, depression, fatigue
- LSD (psychosis in people who have a tendency to it)
- Magic mushrooms (psychosis in people who have a tendency to it)
- Opiates (physical and psychological addiction, constipation)
- PCP (psychosis)
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