What is the lethal dose of zopiclone?

Answer 1

An accurage Lethal Dose for the drug Zopiclone in humans does not seem to be currently available. This information may be useful.

History: A 72-year-old hospitalized male died

following an intentional overdose of 90 milligrams of

zopiclone. The patient was being treated for lung cancer

and died approximately 4 to 10 hours after the ingestion

(Meatherall, 1997). The authors suggested this may be a

minimum lethal dose considering the patient's age,

weakened condition and arteriosclerosis.

Meatherall RC: Zopiclone fatality in a hospitalized

patient. J Forensic Sci. 1997; 42(2):340-3.

LD50/LC50 - ANIMAL DATA - ZOPICLONE

LD50 - (ORAL) RAT: 827 mg/kg

LD50 - (IM) RAT: 295 mg/kg

LD50 - (IV) RAT: 280 mg/kg

LD50 - (SC) RAT: 540 mg/kg

LD50 - (ORAL) MOUSE: 2174 mg/kg

LD50 - (IM) MOUSE: 541 mg/kg

LD50 - (IV) MOUSE: 321 mg/kg

LD50 - (SC) MOUSE: 888 mg/kg

Source: RTECS Registry of Toxic Effects of Chemical Substances.

National Institute for Occupational Safety and ealth,

Cincinnati, O (internet Version). Micromedex Inc.,

Greenwood Village, CO, 2001.

I can tell u that during my drug abuse days I once did 58 7.5 mg pills so 435mg and blackedout. I woke up after I'm not sure how many hours of "sleep" and found i could barely think and standing up was impossible. I'm 21 and 186lbs so it all depends. Worst part about it after the first 8 pills i didnt even realize i was hurting myself or think of the possibilites. Zopiclonse really impairs u i just kept taking more and more

Answer 2

An accurage Lethal Dose for the drug Zopiclone in humans does not seem to be currently available. This information may be useful.

History: A 72-year-old hospitalized male died

following an intentional overdose of 90 milligrams of

zopiclone. The patient was being treated for lung cancer

and died approximately 4 to 10 hours after the ingestion

(Meatherall, 1997). The authors suggested this may be a

minimum lethal dose considering the patient's age,

weakened condition and arteriosclerosis.

Meatherall RC: Zopiclone fatality in a hospitalized

patient. J Forensic Sci. 1997; 42(2):340-3.

LD50/LC50 - ANIMAL DATA - ZOPICLONE

LD50 - (ORAL) RAT: 827 mg/kg

LD50 - (IM) RAT: 295 mg/kg

LD50 - (IV) RAT: 280 mg/kg

LD50 - (SC) RAT: 540 mg/kg

LD50 - (ORAL) MOUSE: 2174 mg/kg

LD50 - (IM) MOUSE: 541 mg/kg

LD50 - (IV) MOUSE: 321 mg/kg

LD50 - (SC) MOUSE: 888 mg/kg

Source: RTECS Registry of Toxic Effects of Chemical Substances.

National Institute for Occupational Safety and ealth,

Cincinnati, O (internet Version). Micromedex Inc.,

Greenwood Village, CO, 2001.

I can tell u that during my drug abuse days I once did 58 7.5 mg pills so 435mg and blackedout. I woke up after I'm not sure how many hours of "sleep" and found i could barely think and standing up was impossible. I'm 21 and 186lbs so it all depends. Worst part about it after the first 8 pills i didnt even realize i was hurting myself or think of the possibilites. Zopiclonse really impairs u i just kept taking more and more