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I had two lots of double cortisone injections into a frozen shoulder last year. On both occasions I had a very extended bleed on my next menstruation, the first time for 7 weeks, the second for 6 weeks, the bleeding only stopping with the prescription of further hormones from my GP. The bleed was not heavy, but very persistent and tiresome. As soon as the cortisone wore off, the extended menstrual bleeding stopped.

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16y ago
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15y ago

I have personally found that it does. And the last time I had one my doctor said it would as I mentioned I'm trying to get pregnant. And sure enough I got my period a week early, don't think I ovulated, and it was a very light period. Its annoying, however, that doctors don't inform you of all the side effects because I also experienced mood swings and insomnia after the last one....

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9y ago

Cortisone injections can affect the menstrual cycle. A side effect of this injection can be irregular or missed menstrual periods. Some other side effects are anxiety, a flushed face, bruising at injection site, or headaches.

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13y ago

I have recently gone thru this issue - a cortisone shot and then two weeks later a period after three yrs without one. A trip to the gyno and a stransvaginal sonogram and an endometrial biopsy have come back inconsequential; signs point to the cortisone shot as the cause at this point. WOW -- a side effect nobody warned ME about, that's for sure. The more I research this, the more unsettled I become. My shoulder doc is a woman, too. You would think SHE would have a clue! Kinda scary...

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11y ago

It might. I hadn't had a period for 1-1/2 years, and 2 weeks after an epidural, I had a period which lasted almost 2 weeks. I'm going for testing now to see if it's anything else (just to be on the safe side), but my gyn is suggesting this might be from the epidural. Sure wish the doctor told me this!

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12y ago

Yes.. Mine did.. I recived shot while on my period and it stopped within the hour..

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7y ago

Yes. Go to ncbi.nlm.nih.gov and look for pubmed 23816843

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