Awakenings 1990, directed by Penny Marshal. Awakenings is a 1990 drama film based on Oliver Sacks' memoir of the same name. It tells the true story of Oliver Sacks, fictionalized as American Malcolm Sayer and played by Robin Williams who, in 1969, discovers beneficial effects of the then-new drug L-Dopa. He administered it to catatonic patients who survived the 1917-1928 epidemic of encephalitis lethargica. Leonard Lowe (played by Robert De Niro) and the rest of the patients were awakened after decades of catatonic state and have to deal with a new life in a new time.
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Robert Redford has starred in many movies. The Sting, The Graduate, The Great Gatsby, The Great Waldo Pepper, Jeremiah Johnson and The Candidate are just of a few famous movies starring Robert Redford.
They starred in two movies together: "Red Dawn" from 1984 and "Dirty Dancing" from 1987.
http://en.wikipedia.org/wiki/James_Stewart_filmography approx. 84 films
Matt Damon and Leonardo DiCaprio starred together in The Departed.
Robert Pattinson has only starred in the Twilight Saga with Kristen Stewart. He has said, that he saw her in her role as Tracy in "Into the Wild" and decided to audition for Twilight after hearing she was going to be in it.