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Any polymerase (DNA or RNA) works in the 5`-3` direction (downstream) because the 3` end contains the hydroxyl groups. The 5` phosphate binds covalently with the 3` hydroxyl group forming a phospho diester linkage.

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Q: Why does RNA polymerase work in direction 5' to 3' not from 3' to 5'?
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Where does the RNA polymerase moves down?

RNA polymerase catalyze the synthesis of RNA by copying the DNA. It occurs in the 5' to 3' direction(moves down).


What direction does RNA polymerase move along the DNA?

Nucleotides are being added as RNA polymerase moves along the DNA template strand.


In which direction does RNA polymerase read a DNA strand?

The correct answer is: RNA is synthesized by RNA polymerase that reads one strand of DNA. RNA polymerase reads DNA 3' to 5'. When RNA is made, it is made 5' to 3'. Most polymerases have the 3' to 5' "reading" activity. The created RNA strand is identical to the coding strand of DNA, which is also in the orientation of 5' to 3'.


What are the different types of RNA polymerases and their promoters?

rma polymerase 1, rna polymerase 2, rna polymerase 3


RNA polymerase moves in which direction along the DNA?

3'-5' along the template strand


What is the direction of synthesis of the new strand?

The template strand (DNA) is read by RNA polymerase in the 3'-5' direction. First, RNA polymerase binds to an A-T rich promoter on the DNA which is upstream from the site of translation. Because A-T bonds are weaker than C-G bonds, the double helix opens up at this point and RNA polymerase begins translation. While translaing the DNA template strand, it creates a complementory mRNA strand and thus the Mrna will read 5'-3' with new bases being added at the 3' end.


Why does DNA replication have to be in an anti-parallel direction?

DNA polymerase III can only work in the 5' to 3' direction.


What are the similarities between rna polymerase and DNA polymerase?

Both RNA and DNA form in the same manner. They add bases to the 3' end of the base to form a polymer.


What enzyme attaches RNA nucleotides the the exposed 3' end of a growing mRNA transcript?

RNA Polymerase


What are the similarities between DNA polymerase and RNA polymerase?

Both RNA and DNA form in the same manner. They add bases to the 3' end of the base to form a polymer.


Explain the role of RNA polymerase in mRNA sythesis?

During transcription, RNA Polymerase binds with upstream of the gene that is to be transcribed into mRNA. This causes the double helix shape of the DNA to unwind. Then, RNA Polymerase uses the template strand of the DNA as guide and synthesizes a complementary mRNA strand using ribonucleotides. Basically, without RNA Polymerase, mRNA would not be synthesized.


Why eukaryotes need 3 RNA polymerase?

Each of the 3 RNA polymerase in eukaryotes perform a different function. For example, RNA pol 2 is involved in mRNA synthesis, RNA pol 1 synthesizes most rRNAs and RNA pol 3 synthesizes tRNNA, the 5S rRNA and other small nuclear RNAS. Eukaryotes are more complex than prokaryotes, hence why eukaryotes would require more RNA polymerases.