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Christa Mcauliffe, who did not survive the trip- killed when the Challenger exploded on the way up. She was the first American woman to lose her life in a spacecraft accident- which strictly speaking, did not happen in space- but inside the atmosphere. There were two females also on the Columbia crew- another All-Hands fatal incident, which broke up on re-entry. Mrs. Mcauliffe was a social studies teacher- apart from NASA- not a Biologist which might have been a better choice.

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Q: Who was the first teacher to fly on a space shuttle?
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