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Cytoplasmic fluorescence is when the cytoplasm of the cell (everything inside the cellular membrane except the nucleus) is lighting up or showing color through under a certain kind of light or microscope, depending on the process. This usually happens when a researcher wants to detect if there is a certain substance in the cell, he can put a fluorescent protein inside the cell that will bind with the substance he is looking for. If the substance is found in the cell, the fluorescent protein will stick to it and let off light or color.

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Q: What does the presence of cytoplasmic fluorescence mean?
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