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It lowers triglycerides and raises HDL
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∙ 13y ago
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Can you take gemfibrozil with simavastatin?
NO
What is another name for gemfibrozil?
Lopid
What is another name for Lopid?
Gemfibrozil
Can gemfibrozil cause cancer?
Studies in animals and humans suggest that gemfibrozil increases the risk of some types of cancer. The drug may also cause gallstones or muscle problems.
What is gemfibrozil 600 mg used for?
to treat high cholesterol
Can gemfibrozil cause birth defects?
The effects of this drug have not been studied in pregnant women. Women who are pregnant or who may become pregnant should check with their physicians before using gemfibrozil.
What happens if you take gemifrozil?
Gemfibrozil is a drug that is prescribed to reduce fat levels. If you take Gemfibrozil, what could happen is that your risk of getting cancer is increased, you may experience musculoskeletal pain and low blood potassium.
Can you breast feed on gemfibrozil?
It is not recommended. However, speak with your doctor, as you may be able to come off them or take alternative medication while you are breastfeeding.
How does gemfibrozil affect breastfeeding?
Whether this drug passes into breast milk is not known. But because animal studies suggest that it may increase the risk of some types of cancer, women should carefully consider the safety of using it while breastfeeding.
What is brand name for the medication Demsibrozil used to treat multiple endocrine neoplasia?
There is no medication with the brand name Demsibrozil used to treat multiple endocrine neoplasia. Treatment for multiple endocrine neoplasia typically involves surgery to remove tumors or hormone-blocking medications.
Should you take gemfibrozil continuously?
Gemfibrozil (Lopid) is a drug that is used to treat high triglycerides. Typically, it is a drug that is taken continuously. During the first year of treatment, your physician will periodically do blood tests to look for rare blood problems or liver damage, then yearly thereafter. If you are later started on (or are currently taking) any of the statin drugs [Lipitor, lovastatin, pravastatin, simvastatin, or Lescol], you should watch for diffuse muscle aches or dark, tea-colored urine. Should any of these, or other bothersome side effects, result, contact your doctor immediately. There is a known, but manageable, drug interaction between the statins and fibrates. They are often used together because the fibrates work best on triglycerides and the statins work best to lower LDL.
Familial dysbetalipoproteinemia?
DefinitionFamilial dysbetalipoproteinemia is a disorder passed down through families in which there are high amounts of cholesterol and triglycerides in the blood.Alternative NamesType III hyperlipoproteinemia; Deficient or defective apolipoprotein ECauses, incidence, and risk factorsA genetic defect causes this condition. The defect results in the buildup of large lipoprotein particles that contain both cholesterol and triglycerides, a type of fat. The disease is linked to defects in the gene for apolipoprotein E in many cases.Hypothyroidism, obesity, or diabetes can make the condition worse. Risk factors for familial dysbetalipoproteinemia include a family history of the disorder or coronary artery disease.SymptomsSymptoms may not be seen until age 20 or older.Yellow deposits of fatty material in the skin called xanthomas may appear on the eyelids, palms of the hands, soles of the feet, or on the tendons of the knees and elbows.Atherosclerosisdevelops at an early age. There may be early chest pain (angina) or decreased blood flow to specific parts of the body, causing transient ischemic attacks of the brain or peripheral artery disease with claudication.Signs and testsTests that may be done to diagnose this condition include:AngiogramGenetic testing for apolipoprotein E (apoE)Heart stress testTotal cholesterolTriglyceride levelVery low density lipoprotein (VLDL) testTreatmentThe goal of treatment is to control underlying conditions such as obesity, hypothyroidism, and diabetes.Reducing calories, saturated fats, and cholesterol may significantly reduce cholesterol levels.See also: Heart disease and dietIf high cholesterol and triglyceride levels continue despite diet changes, your doctor may recommend medication to lower your triglyceride and cholesterol levels. Medicine to lower blood triglyceride and cholesterol levels include:Bile acid-sequestering resinsFibrates (gemfibrozil, fenofibrate)Nicotinic acidStatinsExpectations (prognosis)People with this condition have an increased risk for coronary artery disease and peripheral vasculardisease.With treatment, most people show a significant reduction in lipid levels.ComplicationsHeart attackStrokePeripheral vascular diseaseIntermittent claudicationGangrene of the lower extremitiesCalling your health care providerCall your health care provider if you have been diagnosed with this disorder and:New symptoms developSymptoms do not improve with treatmentSymptoms get worsePreventionScreening the family members of those with familial dysbetalipoproteinemia may lead to early detection and treatment.Early treatment and avoiding other risk factors for vascular disease (such as smoking) are crucial to preventing early heart attacks, strokes, and blocked blood vessels.ReferencesMahley RW, Weisgraber KH, Bersot TP. Disorders of lipid metabolism. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 36.Semenkovich CF. Disorders of lipid metabolism. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 217.
