What does gemfibrozil do?

Updated: 9/27/2023
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It lowers triglycerides and raises HDL

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Q: What does gemfibrozil do?
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Can you take gemfibrozil with simavastatin?


What is another name for gemfibrozil?


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Can gemfibrozil cause cancer?

Studies in animals and humans suggest that gemfibrozil increases the risk of some types of cancer. The drug may also cause gallstones or muscle problems.

What is gemfibrozil 600 mg used for?

to treat high cholesterol

Can gemfibrozil cause birth defects?

The effects of this drug have not been studied in pregnant women. Women who are pregnant or who may become pregnant should check with their physicians before using gemfibrozil.

What happens if you take gemifrozil?

Gemfibrozil is a drug that is prescribed to reduce fat levels. If you take Gemfibrozil, what could happen is that your risk of getting cancer is increased, you may experience musculoskeletal pain and low blood potassium.

What is brand name for the medication Demsibrozil used to treat multiple endocrine neoplasia?


Can you breast feed on gemfibrozil?

It is not recommended. However, speak with your doctor, as you may be able to come off them or take alternative medication while you are breastfeeding.

How does gemfibrozil affect breastfeeding?

Whether this drug passes into breast milk is not known. But because animal studies suggest that it may increase the risk of some types of cancer, women should carefully consider the safety of using it while breastfeeding.

Should you take gemfibrozil continuously?

Gemfibrozil (Lopid) is a drug that is used to treat high triglycerides. Typically, it is a drug that is taken continuously. During the first year of treatment, your physician will periodically do blood tests to look for rare blood problems or liver damage, then yearly thereafter. If you are later started on (or are currently taking) any of the statin drugs [Lipitor, lovastatin, pravastatin, simvastatin, or Lescol], you should watch for diffuse muscle aches or dark, tea-colored urine. Should any of these, or other bothersome side effects, result, contact your doctor immediately. There is a known, but manageable, drug interaction between the statins and fibrates. They are often used together because the fibrates work best on triglycerides and the statins work best to lower LDL.

Familial hypertriglyceridemia?

DefinitionFamilial hypertriglyceridemia is a common disorder passed down through families in which the level of triglycerides (a type of fat) in a person's blood are higher than normal.The condition is not associated with a significant increase in cholesterol levels.Causes, incidence, and risk factorsFamilial hypertriglyceridemia is caused by a genetic defect, which is passed on in an autosomal dominant fashion. This means that if you get a bad copy of the gene from just one of your parents, you will have the condition.Some people with this condition also have high levels of very low density lipoprotein (VLDL). The reason for the rise in triglycerides and VLDL is not understood.Familial hypertriglyceridemia does not usually become noticeable until puberty or early adulthood. Obesity, hyperglycemia (high blood glucose levels), and high levels of insulin are often also present and may cause even higher triglyceride levels.Familial hypertriglyceridemia occurs in about 1 in 500 individuals in the United States. Risk factors are a family history of hypertriglyceridemia or a family history of heart disease before the age of 50.SymptomsYou may not notice any symptoms. People with the condition may have coronary artery disease at an early age.Signs and testsPeople with a family history of this condition should have blood tests to check very low density lipoprotein (VLDL) and triglyceride levels. Blood tests usually show a mild to moderate increase in triglycerides (about 200 to 500 mg/dL).A coronary risk profile may also be done.TreatmentThe goal of treatment is to control conditions that can raise triglyceride levels such as obesity, hypothyroidism, and diabetes.Your doctor may tell you not to drink alcohol. Because certain birth control pills can raise triglyceride levels, you should carefully discuss their use with your doctor.Treatment also involves avoiding excess calories and foods high in saturated fats and carbohydrates. See also: Heart disease and dietIf high triglyceride levels persist despite diet changes, medication may be needed. Nicotinic acid, gemfibrozil, and fenofibrate have been shown to lower triglyceride levels in people with this condition.Expectations (prognosis)Persons with this condition have an increased risk of coronary artery disease and pancreatitis.Losing weight and keeping diabetes under control helps improve the outcome.ComplicationsPancreatitisCoronary artery diseasePreventionScreening family members for high triglycerides may detect the disease early.ReferencesMahley RW, Weisgraber KH, Bersot TP. Disorders of lipid metabolism. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 36.Semenkovich CF. Disorders of lipid metabolism. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 217.