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The obvious asnwer here is the liver, medicaly it's probably worst off, but with the addiction and drastic personality change the brain may never be able to opperate the same again. people who were nice for years, even after they have been clean for a year can still show drastic personality changes.

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Q: The organ most affected by the long-term abuse of alcohol is?
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Which organ of the body is affected first by alcohol?

I think the first organ to be affected by alcohol is your liver.


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