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EzraNo. Unlike aspirin and other non-steroid anti-inflammatory drugs NSAIDs such as ibuprofin, Paracetamol acts in the brain, blocking an enzyme involved in the transmission of pain. Paracetamol is a popular analgesic and antipyretic drug used for relieving fever, headaches, and other minor aches and pains.
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How is paracetamol soluble in water?
Paracetamol is soluble in water because it forms hydrogen bonds with water molecules. These hydrogen bonds allow for the paracetamol molecules to dissociate and mix well with water, allowing for the medication to dissolve easily when taken orally.
What is the paracetamol's antagonist drug?
The antagonist of paracetamol is N-acetylcysteine, which is used as an antidote in cases of paracetamol overdose. N-acetylcysteine helps to replenish depleted glutathione levels in the liver, which is essential for detoxifying the metabolites of paracetamol.
Is paracetamol a neutral molecule?
Yes.
What is the standard partition coefficient of paracetamol?
The partition coefficient of paracetamol is reported to be around 0.36 at pH 7.4.
Does paracetamol contain an amide group?
No, paracetamol (acetaminophen) does not contain an amide group in its chemical structure. It contains a benzene ring with hydroxyl and acetamide groups.
