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April 21, 2011.Andre Romelle Young (born February 18, 1965), primarily known by his stage name Dr. Dre has Lipodystrophy The exact mechanism of HIV-associated lipodystrophy is not fully elucidated. However, on the one hand, it is believed to be caused by anti-retroviral medications. Lipodystrophy seems to be mainly due to HIV-1 protease inhibitors. Interference with lipid metabolism is postulated as pathophysiology. Also, the development of lipodystrophy is associated with specific nucleoside reverse transcriptase inhibitors (NRTI). Mitochondrial toxicity is postulated to be involved in the pathogenesis associated with NRTI ATLEAST QUINCY JONES DON'T SH*T ON DI*KS,he DOUCHES FIRST!

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14y ago

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