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First of all, I am not a doctor, so what follows is just my opinion. If you are taking quetiapine (Seroquel), then you should talk to the prescribing physician before taking any supplements, especially ones that can be sedating or otherwise affect neurotransmitter levels (5-HTP does both).

That said, I am taking citalopram (Celexa), an SSRI (selective serotonin reuptake inhibitor), along with a low dose (25mg) of quetiapine. My doctor said that this is a safe combination that they use frequently and with good results. So my guess is that if you are taking a low dose of quetiapine for sleep, as I am, your doctor will be okay with you taking 5-HTP along with it. If you are actually using quetiapine for it's proper function as an antipsychotic, you'll be taking a much higher dose than me; that could be an issue, since quetiapine DOES affect several 5-HT (serotonin) receptors.

New AnswerNo don't do it. I did it and had to go to the hospital. Also seroquel is a risky drug with lots of side effects so you should check with your doctor about better sleeping pills like benedryls or something. End New AnswerNew Answeri am just a normal user / not a doctor, but i just had a bad experience (DON'T MIX THESE) last night, Seroquel + 5-HTP. i believe it leads to what can googled as "Serotonin Syndrome". mine was minor, because i took extremely small doses of each (thank God), but otherwise i could see that getting 'stomach-pumped' bad, or whatever. it was 0 enjoyable & i got no sleep. don't mix.
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13y ago
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9y ago

No, you should not take these 2 medications together because they both are in the same class of drug and treat the same things. These drugs are used to treat depression and fibromyalgia.

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11y ago

sorry

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Q: Can you take Seroquel and 5 HTP together?
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