To inoculate means to inject a micro-organism into something, as in vaccines or inoculating plants with certain experimental micro-organisms. The doctor will inoculate you against smallpox with a vaccine.

It can also mean to make someone become full of a certain quality. The politician will inoculate everyone with the idea that freedom must be fought for.
I will inoculate the next patient with a dose of oral polio vaccine.
Definition: (v.) to treat with the objective of producing resistance to a disease.

Sentence: 'The doctor gave Joe a shot to inoculate him for the flu.'