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Aminoglycosides inhibit the release of acetylcholine from the motor nerve. Myestenia gravis patients are more susceptible to this effect. So these drugs are to be avoided in myestenia gravis patients.

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Q: Why aminoglycosides cause weakness in myasthenia gravis?
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What are the causes of a droopy eyelid?

Some common lid problems include the following: stye, blepharitis, chalazion, entropion, ectropion, eyelid edema, and eyelid tumors.


In myasthenis gravis what cellular receptors are affected?

Acetylcholine receptors at neuromuscular junctions are affected in MG. MG is an autoimmune disorder in which the body produces antibodies against its own protein, the acetylcholine receptor. These antibodies block the receptor, preventing the binding of acetylcholine and inhibiting the function of the receptor, which is to initiate a depolarization in muscle cells that will lead to contraction. Fewer available acetylcholine receptors means greater stimuli, i.e. more acetylcholine has to be released to cause a contraction. This manifests physically as serious weakness resulting from inability to move muscles at will. The name of the disease describes the symptoms quite well (my-, muscle; -a-, without; -sthenia, strength; gravis, heavy, serious).


Ototoxicity and nephrotoxicity are caused by what?

Main Drugs/Classes are: Cisplatin Loop Diuretics Aminoglycosides Vancomycin Edit: <<While I'm sure many things cause otoxicity and nephrotoxicity; the major example that springs to mind is aminoglycocides (gentomicin/streptomicin)>>


A deterioration in the myelin sheaths of motor axons to the lower leg would be expected to?

Cause leg pain and weakness


What could cause stinging pain and weakness in upper left arm?

stroke or heart attack, if that answers yurr question

Related questions

Is myasthenia gravis a group of inherited muscle disorders that cause muscle weakness without affecting the nervous system?

Myasthenia gravis is a neuromuscular disorder involving the muscles and the nerves that control them.


What is a chronic autoimmune disorder in which the motor neurons fail to transmit impulses to the muscles to cause muscle contractions?

A chronic autoimmune disease that affects the neuromuscular junction is myasthenia gravis. It leads to fluctuating muscle weakness and fatigue.


What is the reason for an enlarged thymus gland?

Myasthenia gravis is one cause


Does polyvinyl chloride cause myasthenia gravis?

Although polyvinyl chloride (PVC) is associated with some health effects, through Phthalates, they are usually either breast cancer and endocrine disruptions. Myasthenia Gravis is when the neurotransmitter acetylcholine is blocked in the eye, causing eye muscles to become relaxed and either partially or completely uncontrollable. It is unlikely that PVC cause myasthenia gravis.


A deficiency of ACh receptors in a motor end plate would cause and is called?

myasthenia gravis


What is a disease that can affect the thymus gland?

Scientists beleive that disorder of thymus gland can cause Myasthenia Gravis , a disease of severe muscle weakness . In this antibodies are produced against Ach receptors of neuro-muscular junction .


What do people with myasthenia gravis lack?

People with MG suffer with debilitating muscle weaknesses in their arms, legs, face, throat, hands and eyes. The symptoms of muscle weakness may occur at any time but most often after normal use of the extremities, i.e. Taking a walk may cause leg weakness and reading a book may cause eye weakness


What is the mortality rate due to respiratory failure associated with myasthenia gravis?

In a few cases, the severe weakness of MG may cause respiratory failure, which requires immediate emergency medical care. Advances in medical care have reduced the mortality rate to about 3%.


Which medical conditions can cause myasthenia gravis?

10 percent of patients have a tumor in the thymus, that is usually benign, and 70% have changes that indicate an active immune response.


Can Myasthenia Gravis kill you?

no, not unless something happens because of it ex respiratory failure.


What can be the cause of new onset palsies in adults?

New onset palsies in adults can stem from myasthenia gravis, diabetes, meningitis, microvascular disease (atherosclerotic vascular disease) or giant cell arteritis (arterial inflammation).


Is myasthenia gravis caused by herpes?

Myasthenia Gravis is an autoimmune disease of the neuromuscular system that is characterized by high plasma levels of acetylcholine receptor (AChR) antibodies, which invoke an immune response against these receptors. Production of these antibodies are caused by molecular mimicry of a self antigen. T-helper cells, a type of immune system cells, can come across antigen presenting cells that display an antigen that is similar, in sequence, to AChR's. The T-helper cells are activated in this manner and can cause an immune response (antibody production) against AChR's. In essence, the Herpes virus is known to have a similar sequence to AChR's, therefore, the existance of the Herpes virus increases the risk of Myasthenia Gravis development.