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Adrenaline has no withdrawal effects, but often the energy spent as a result of the fight-or-flight response can cause the tiring. However, because adrenaline increases blood flow to skeletal muscle, other organs may have impaired functioning for a period of time, but it probably isn't enough to cause any long-term impairments.

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Q: When adrenaline is released into your body does it make you tired after you are done having it in your blood stream?
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