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The vaccine that left a circular mark on some people's arms was the smallpox vaccination. Not all people got the mark. Some have the mark on their arm because they fussed over the vaccination site and sometimes the people jerked when they were pricked with the needle. The needle was not injected deeply into the muscle but pricked at the surface of the arm.

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14y ago
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10y ago

Smallpox vaccine left a scar on the arm. It was given into the 1960s.

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Q: What is the vaccine that left a mark on arms?
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