It is derived from a preprohormone precursor that is synthesized in the hypothalamus and stored in vesicles at the posterior pituitary. Most of it is stored in the posterior pituitary to be released into the bloodstream; however, some AVP is also released directly into the brain.
AVP IS ALSO CALLED ADH....
the main target is the distal tubule of the kidney =)
because it (undirectly) aids in water reabsorption, it would only make sense to target the kidney
aldosterones main purpose is sodium re-absorption, so it would target the distal tubule because that's where sodium leaves
It act on the kidneys.Mainly on the distal convoluted cells
Angiotensin, Aldosterone, ADH, and ANP.
Aldosterone will cause Na+ to be absorbed from a filtrate
Aldosterone promotes water retention and reduces urine volume
Aldosterone helps to indirectly regulate blood levels. A low sodium diet is a way to increase aldosterone in the body.
It decreases the affect of aldosterone secretion.
Aldosterone is a hormone, so it gets to the kidneys via the blood stream.
The target cells of aldosteron are in the distal convulated tubules. Aldosteron there spreads into the cells, makes complexes with the receptors of the nucleus and codes for genes that are responsible for the proteins (e.g. sodium permease) and ferments (citratsintase, carboanhidrase) that are important for the transfer of sodium ions.
Aldosterone is sensitive to a few different things. The main thing it is sensitive to is the kidneys.
Aldosterone causes sodium to be retained and potassium to be excreted and blood pressure to rise.
ADT
Aldosterone
Aldosterone is regulated by negative feedback system except in cases of dehydration in which high sodium levels stimulate more production of aldosterone. Normally negative feedback regulates production.