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Topoisomerase: are isomerase enzymes that act on the topology of DNA
Helicase untwists the double helix and separates the template DNA strands at the replication fork. This untwisting causes tighter twisting ahead of the replication fork, and topoisomerase helps relieve this strain
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∙ 15y ago
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∙ 14y agoIt cleaves both strands of the DNA helix during DNA replication and transcription.
This relieves the torsional stress during DNA unwinding. After DNA has unwound, it helps reconnect (religate) the double stranded DNA, restoring the DNA chain integrity.
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∙ 13y agoThe function of topoisomerase is to unwind the helix of DNA into a regular, ladder-like shape. Topoisomerase is only found in primates. In other organisms, the molecule is called gyrase that unwinds the DNA.
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∙ 14y agoThis torsional stress is relieved by the enzymes DNA topoisomerases. Topoisomerases relieve torsional stresses in duplexes of DNA by introducing either double- (topoisomerases II) or single-stranded (topoisomerases I) breaks into the backbone of the DNA. These breaks allow unwinding of the duplex and removal of the replication-induced torsional strain. The nicks are then resealed by the topoisomerases.
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Wiki User
∙ 13y agoIt's the relieving strand in the DNA ahead of the replication fork
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∙ 14y agoTopoisomerases disattach and reattach DNA. It is required for DNA to reproduce>
Sydni McDonald
What is the role of dna ligase during replication
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What is the difference between helicase and topoisomerase?
Helicase unwind the two DNA strands while topoisomerase unwind and also rejoin the the two strands of DNA.
Is topoisomerases belong to restriction enzymes?
Topoisomerase is not a restriction enzyme but an enzyme that keeps unwound DNA from tangling while it is being replicated.
What enzyme cuts and seals DNA?
HaeIIIrestriction enzymes
Which is the role of photosynthesis II in the light reactions?
It has to make two products, Those are ingredients of the dark reaction.
What enzyme catalyzes DNA replication?
one of them is heliocase. it 'unzips' the DNA strand. You can always remember this because it's in a popular joke: Q. Why is the enzyme heliocase a lot like a teenage boy? A. They both want to unzip your jeans (genes) !!!!!
How does topoisomerase affect the DNA strand during DNA replication?
The topoisomerase enzyme uncoils the double helical structure of DNA during its replication to form the replication fork. In eukaryotes both posive and negative supercoils get unbind by topoisomerase I & II respectively.Topoisomerase isomerase unwinds DNA to form replication fork
What enzyme is responsible for breaking the hydrogen bonds between the two strands and unwinding the helix?
Helicases and gyrases both function to uncoil the supercoiling of the two DNA strands. Moreover, gyrase is responsible for adjusting the tension in the two strands so that they don't snap while unraveling.
What has the author Leonardo Salmena written?
Leonardo Salmena has written: 'The cell cycle-dependent regulation of DNA topoisomerase II[alpha] expression is mediated by proteasomal degradation'
What is the difference between helicase and topoisomerase?
Helicase unwind the two DNA strands while topoisomerase unwind and also rejoin the the two strands of DNA.
What breaks covalent bonds in DNA backbone?
Topoisomerase
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Role Play - 2010 II was released on: USA: 6 November 2010
What is the enzyme responsible for conversion of negatively supercoiled DNA into relaxed circular DNA?
Topoisomerase 1
What genre is EverQuest II: The Shadow Odyssey?
The genre of EverQuest II: The Shadow Odyssey is Role Playing.
What role did restoration play in England?
The return of Charles II.
What was America and role in World World II?
arms and aid
What was the role of Czar Nicholas II during the 1900s?
he was the emperor
What was nicholas II role in the Russian revolution?
the ruler of russia
