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When you are on methatrexate it tends to deplete the folic acid in your body which can be bad for the kidney. I myself take 10 mg of MTX once a week to help stop inflammation that is the result of Rheumatoid arthritis's. to build up the folic acid I take 5mg of Megafol Folic acid every day. In any case you should speak to your doctor as Methatrexate can be a dangerous drug if there are any problems.

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Leucovorin is the medication that is used as a rescue therapy from toxicity of methotrexate.

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Leucovorin

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Q: What drugs are used as a RESCUE from toxicity of methotrexate?
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What are the Cytotoxic drugs used in skin diseases?

Methotrexate is an example of cytotoxic drug to treat skin disorder such as Psoirasis.


What is leucovorin typically used for?

Leucovorin is typically used as a rescue medication to reduce the toxic effects of high-dose methotrexate chemotherapy. It helps protect healthy cells in the body from the harmful effects of methotrexate by acting as a "rescue" folate supplement. It is also used in the treatment of anemia caused by folate deficiency.


Can you take Tylenol and methotrexate?

caution Due to aspirin's effect on platelet aggregation and GI mucosa, aspirin should be used cautiously in patients with thrombocytopenia following treatment with antineoplastic agents due to an increased risk of bleeding.[5717] In general, because certain antineoplastic agents can cause clinically significant thrombocytopenia, they may increase the risk of aspirin-associated bleeding (i.e. GI bleeding, inhibited platelet aggregation, and prolonged bleeding time). Also, aspirin may mask signs of infection such as fever and pain in patients following treatment with antineoplastic agents or immunosuppressives.[6859] Aspirin, ASA should be used with caution in patients receiving immunosuppressive therapy. Although usually seen with large salicylate doses, aspirin may displace mercaptopurine, 6-MP from secondary binding sites, resulting in bone marrow toxicities and blood dyscrasias.[5232] Special consideration should be given to myelosuppressed patients prior to receiving aspirin. Due to the thrombocytopenic effects of methotrexate,[5067] when used as an antineoplastic agent, an additive risk of bleeding may be seen in patients receiving concomitant anticoagulants, platelet inhibitors (also see salicylates), strontium-89 chloride, or thrombolytic agents. Caution should be exercised when salicylates are given in combination with methotrexate. Since both are weak acids, salicylates can impair the renal secretion of methotrexate and increase the risk of methotrexate toxicity. Salicylates can also displace methotrexate from protein-binding sites.[5067] Although the risk for drug interactions with methotrexate is greatest during high-dose methotrexate therapy, it has been recommended that any of these drugs be used cautiously with methotrexate even when methotrexate is used in low doses for the treatment of rheumatoid arthritis. A significantly higher incidence of leukopenia has been reported in patients taking aspirin during methotrexate therapy. Bismuth subsalicylate may have similar effects. In addition, large doses of salicylates (>= 3-4 g/day) can cause hypoprothrombinemia,[5170] an additional risk factor for bleeding. Caution should be exercised when aspirin is given in combination with methotrexate. Concomitant administration of salicylates with high-dose methotrexate therapy has been reported to elevate and prolong serum concentrations of methotrexate resulting in deaths from severe hematologic and gastrointestinal toxicity. Although the risk for drug interactions with methotrexate is greatest during high-dose methotrexate therapy, it has been recommended that any salicylate be used cautiously with methotrexate even when lower doses of methotrexate are given for the treatment of rheumatoid arthritis or psoriasis. Elderly patients and patients with renal impairment may be at particular risk. As both methotrexate and salicylates are weak acids, aspirin can impair the renal secretion of methotrexate and increase the risk of methotrexate toxicity. Salicylates can also displace methotrexate from protein-binding sites.[5067] [5232]


What drugs are used in chemotherapy for Hodgkin's disease?

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What type of medication is used to treat cough of a patient with a malignant throat mass?

There are many drugs that can be used in the treatment of a malignant throat mass. Some of these are methotrexate sodium, carboplatin, trexall, and rheumatrex.


When was Methotrexate first used?

1987


Is methotrexate a chemo medicine?

No, methotrexate is a form of chemotherapy and an immunosuppressant. It is used to treat autoimmune disease and some forms of cancer.


What factor calls for the limited use of some pain decreasing drugs?

Owing to toxicity over the long term, some drugs can only be used for acute pain or as adjuncts in chronic pain management.


What is the drug interactions associated with floxglove?

May increase toxicity of other cardioactive drugs. Not to be used with diuretics, amphetamines, medication for respiratory problems. And more . . .


Is Methotrexate safe in it's present generic from Barr Mfg Bad results have been experienceed?

Methotrexate is metho trexate regardless of whose name is on it unless it is not made according to specification's. The stuff is nasty in any case and should be used with great care I only take 15mg once a week and have to be regularly tested for kidney toxicity. not to mention the other hundred + side effects.


Can you take Zoloft and methotrexate?

This would be OK to do. There are no interactions listed between these two drugs. Remember that methotrexate is very harsh on your stomach. Have some food before you take this! Even more important to remember is that methotrexate wipes out folic acid in the system so a folic acid supplement needs to be taken everyday in order to reduce the risk of liver toxicity.


What is the toxicity of anti-influenza drugs?

The anti-influenza drugs are generally well tolerated. Amantadine, which is also used for treatment of Parkinsonism, may show more frequent CNS effects, including sedation and dizziness.