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Some clinical manifestations include: chronic cough, pancreatic insufficiency, poor weight gain, repeated lung infections, salty tasting skin, and wheezing. There are many other symptoms and they vary considerably from person to person.

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12y ago
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9y ago

Characteristics and symptoms of cystic fibrosis can vary from person to person. However, typical characteristics include a persistent cough, wheezing, recurring lung infections, poor weight gain and constipation.

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15y ago

* Frequent coughing that brings up thick sputum, or phlegm (flem).

* Frequent bouts of bronchitis and pneumonia. They can lead to inflammation and permanent lung damage.

* Salty-tasting skin.

* Dehydration.

* Infertility (mostly in men).

* Ongoing diarrhea or bulky, foul-smelling, and greasy stools.

* Huge appetite but poor weight gain and growth. This is called "failure to thrive." It is a result of chronic malnutrition because you do not get enough nutrients from your food.

* Stomach pain and discomfort caused by too much gas in your intestines. CF can also lead to other medical problems, including: * Sinusitis. The sinuses are air-filled spaces behind your eyes, nose, and forehead. They produce mucus and help keep the lining of your nose moist. When the sinuses become swollen, they get blocked with mucus and can become infected. Most people with CF develop sinusitis.

* Bronchiectasis. Bronchiectasis is a lung disease in which the bronchial tubes, or large airways in your lungs, become stretched out and flabby over time and form pockets where mucus collects. The mucus provides a breeding ground for bacteria. This leads to repeated lung infections. Each infection does more damage to the bronchial tubes. If not treated, bronchiectasis can lead to serious illness, including respiratory failure.

* Pancreatitis. Pancreatitis is inflammation in the pancreas that causes pain.

* Episodes of intestinal blockage, especially in newborns.

* Nasal polyps, or growths in your nose, that may require surgery.

* Clubbing. Clubbing is the widening and rounding of the tips of your fingers and toes. It develops because your lungs are not moving enough oxygen into your blood stream.

* Collapsed lung. This is also called pneumothorax.

* Rectal prolapse. Frequent coughing or problems passing stools may cause rectal tissue from inside you to move out of your rectum.

* Liver disease due to inflammation or blocked bile ducts.

* Diabetes.

* Gallstones.

* Low bone density because you do not get enough Vitamin D

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12y ago

CF causes secretion of abnormally viscous mucus that clogs the respiratory that predisposes the child to respiratory infections. It appears that infection of CF victims' lungs with the bacterium Pseudomonas aeruginosa trips a genetic swithc that causes the disabled cells to churn out oceans of abnormal muchin ( the primary component of mucus). The bacteria then feed on the stagnant pools of mucus and keep sending signals to the cells to make more. Toxins released by the bacteria and the local inflammatory reaction set up by the immune response both damage the lungs. Unable to reach the bacteria embedded in the mucus, the immune cells begain to attack the lung tissue, turning the air sacs into bloated cysts. This can be found in the 8th edition of Human Anatomy & Physiology, page 843

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12y ago

There are no 'Side Effects', just things that 'come with the package'.

You can suffer breathlessness, bowel problems and probalmes with liver and kidneys. There are other things too, but at age 13, that's all I've really had so far.

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12y ago

A symptom of Cystic Fibrosis is difficulty breathing as mucus can block the airways.

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13y ago

which are the most common physical features of cystic fibrosis

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Q: What are the side affects of cystic fibrosis?
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