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What would happen to a resting membrane potential if the sodium potassium transport pump was blocked?
Wiki User
∙ 9y ago
During depolarization, sodium (Na) rushes into the neuron through Na channels (at the Nodes of Ranvier between the bundles of myelin "insulation"). Less Na in the extracellular fluid would mean there would be less to rush in. So, the neuron would not be depolarized as well. The resting membrane potential would be more positive on the inside.
Wiki User
∙ 9y ago
Wiki User
∙ 11y agoIn excitable cells, it would lead to a decrease in the size of the action potential but would have no effect on the resting membrane potential. (Ganong Physiology, Chapter 3)
Wiki User
∙ 9y agoResting membrane potential is maintained as long as the sodium potassium transport pump is functioning properly. If it is blocked, the cell membrane depolarizes.
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