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Methotrexate was originally used in cancer chemotherapy treatments It interferes with the operation of the immune system. It was noted that the use of this drug reduced inflammation in RA sufferers. The amount of methotrexate used to treat RA is far far smaller then that used for chemotherapy and it is still not understood exactly why it has the effect that it has other then it interferes with the immune systems operation. The draw backs in it use are that it can lead to a high degree of toxicity in the system and lead to liver damage if not monitored carefully with regular blood tests. Folic acid is used to help reduce the chance of damage occurring as a result of its use.
Wiki User
∙ 14y ago
Wiki User
∙ 14y agoMethotrexate is an anti-metabolite which interfere with the way cells utilize essential nutrients which inhibits the activity of the immune system. the result of this is that it has the affect of reducing inflammation. As a cytotoxic drug it may also slow the growth of cells in the synovial membranes that line the joints.
Methotrexate used in very low doses, is a long term treatment. Dramatic improvement seems to occur in patients within the first few months followed by Steady improvement, often over months or even years. When the drug is withdrawn signs of improvement disappear and a flare up of symptoms occurs within a few weeks.
Wiki User
∙ 11y agotreatments for Mild psoriatic Arthritis is similar to other forms of arthritis with aspirin, anti-arthritis, anti-arthritis drugs such as indomethacin, and related non-steroidal, anti-inflammatory drugs. usualy if only a few joints are involved, an excellent response can be obtained by the local injection of steroids by a rheumatologist into the affected joints without the need for oral medications.
Severe psoriatic arthritis may be treated successfully with methotrexate. Methotrexate a disease modifying drug can be effective for those patients with severe psoriatic arthritis who do not respond to the standard anti-arthritis medications or those patients who do not tolerate standard anti-arthritis medications and can only tolerate methotrexate.
Wiki User
∙ 13y agoIt is one of the treatments used for rheumatoid arthritis. Due to potentially problematic side effects, treatment with methotrexate should be carefully prescribed and monitored by a rheumatologist.
Wiki User
∙ 14y agoafter using methotrexate what must be the hcg level.How many dose methotrexate need.
Wiki User
∙ 11y agoMTX is used as a disease modifying drug in the case of Rheumatoid arthritis and similar autoimmune diseases. it causes the immune system to become less reactive in the case these diseases.
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How is psoriatic arthritis diagnosed and treated?
Psoriatic arthritis is usually diagnosed in a clinic. A doctor will look for inflammation of the skin which suggests psoriatic arthritis. The treatments are anitinflmmatory cream and exercise.
Is chemotherapy used for treatment other than cancer?
Yes. Methotrexate is now being used as a treatment (low dosage) for some autoimmune diseases, including ankylosing spondylitis, Crohn's disease, psoriasis, psoriatic arthritis, rheumatoid arthritis, and scleroderma.
Is simponi effective without methotrexate?
In the U.S., Simponi is approved as a 50 mg subcutaneous injection once a month and is indicatedIn combination with methotrexate for the treatment of adult patients with moderately to severely active rheumatoid arthritisAlone or in combination with methotrexate for the treatment of adult patients with active psoriatic arthritisFor the treatment of adult patients with active ankylosing spondylitisSimponi is available in two dosage forms. The Simponi SmartJect is a novel autoinjector designed to meet the needs of arthritis patients that has received the Ease-of-Use Commendation by the Arthritis Foundation. Simponi is also available as an easy to use prefilled syringe.
Is instaflex good for psoriatic arthritis?
It helps control inflammation which is responsible for joint damage however this should be used under medical direction.
Is methadone prescribed to someone with Rheumatoid arthritis?
No. you have possibly got it mixed up wit methotrexate which is used to modify the effectiveness of the immune system.
What joints are most commonly affected by Rheumatoid Arthritis?
The joints that are most commonly affected by Rheumatoid Arthritis are the joints most commonly used in everyday usage such as fingers, knees, legs and feet.
What exactly is arthritis?
AnswerThe term arthritisliterally means joint inflammation, but it also is used to refer to more than 100 rheumatic diseases. These diseases can cause pain, stiffness, and swelling in joints and may also affect other parts of the body.Some common types of arthritis are osteoarthritis,rheumatoid arthritis, systemic lupus erythematosus,gout, juvenile rheumatoid Arthritis, ankylosing spondylitis, and psoriatic arthritis.
What analgesic drug is used to treat osteoarthritis but not rheumatoid arthritis?
it is likely that if a person that has RA is taking methotrexate then they wil not be using aspirin. as ther may be a reaction between the two.
What is Methotextrate used for?
Methotrexate is a chemotherapy drug that is used in cancer treatment. It has also been found to be useful in the control of Rheumatoid arthritis. It is referred to as a disease modifying drug in the case of RA. Methotrexate is an immune suppressant that reduces the immune systems ability to produce the cells that cause the inflammation that it typical in RA. When MTX is prescribed should be taken with folic acid as it depletes the system of this and that in turn can bring about kidney damage.
How long a course of chemo for rheumatoid arthritis?
Rheumatoid Arthritis is not treated with chemotherapy, but you may have some confusion about one of the drugs used in the fight against RA -Methotrexate - which in larger doses is primarily used in chemotherapy for cancer.Chemotherapy is intensive, site-specific treatment for cancer patients. In smaller doses it is used to decrease the abnormal behavior of cells in inflammatory & autoimmune diseases, including rheumatoid arthritis. Please see the following article:www.clevelandclinic.org/arthritis/treat/facts/chemo.htmAnswer 2I believe what you are wondering about is a common RA med, Methotrexate, which is a chemo med and commonly used for different types of leukemia. Patients with cancer may receive it intravenously, while RA patients usually take a small amount once a week (orally or by injection). One must also take folic acid when using this drug, as methotrexate depletes this and its absence could lead to liver damage.
When was Methotrexate first used?
1987
What is methotrexate?
Source: rx2040. com Methotrexate is an antimetabolite used to treat certain types of cancer. Methotrexate is an antimetabolite used to treat certain types of cancer. It inhibits dihydrofolate reductase, an important enzyme responsible for the synthesis of nucleotides for DNA. This medication inhibits synthesis of DNA, DNA reparation and cell mitosis. Cells of malignant tumor, bone marrow, embryonic cells, epithelial cells of the intestinal mucosa, bladder, oral cavity are the most sensitive to it. Methotrexate is used in treatment of breast cancer, squamous cell carcinoma of the head and neck, lung cancer, trophoblastic tumor, cervical cancer, ovarian cancer, bladder cancer, colorectal cancer, esophagus cancer, stomach cancer, pancreatic cancer, testicular cancer, acute lymphoblastic leukemia and many others.
