When you are born, the body takes stock of itself, things that are your make-up (hair, nails, skin, tissues, organs, etc.) are 'self', and the rest is 'not self'. When you get a cold or any other virus or bacteria or fungus your immune system attacks it because it is 'not self'.
The problem in Autoimmunity is that the body blurs the line between 'self' and 'not self' and starts attacking 'self' like a virus or something of the like.
Autoimmunity or hypersensitivity.
A low level of Autoimmunity is beneficial, period. High autoimmunity means a person is allergic to himself or herself. The immune system begins to destroy the person it should protect. It is thought to cause arthritis, diabetes, and a host of other diseases.
When the immune system mistakenly attacks a normal part of the body, this is known as autoimmunity. Autoimmunity that causes hypOthyroidism (low thyroid) is called Hashimoto's Thyroiditis. This condition can also cause hypERthyroidism as well. There are specific antibodies in patients with Hashimoto's. Autoimmunity that causes hypERthyroidism is usually a condition known as Graves' Disease. There are specific antibodies in patients with Graves' Disease.
Autoimmunity
A positive ANA test does not necessarily mean the patient has an autoimmune disease. An ANA test is not specific for autoimmunity, but is a sign of inflammation that is often specific to autoimmunity. Specific antibodies are usually tested for to determine if a patient has an autoimmune disease.
Yehuda Shoenfeld has written: 'Natural Autoantibodies' 'The mosaic of autoimmunity' -- subject(s): Autoantibodies, Autoimmune diseases
There are two groups that recognize the protein. The Anti-Hsp65 antibodies recognize M proteins of group A streptococci. They are strong bacterial immunogens that have been linked to arthritis and autoimmunity.
The cause of HAM/TSP is still a matter of debate. Three hypotheses are considered by scientists as the most likely cause of TSP: direct toxicity, autoimmunity, and bystander damage.
Science has identified some genes that appear to be related to the inheritance of lupus and autoimmunity. Having these genes only predisposes the patient to the disease however, it does not mean the patient will ever get lupus.
Guido Kroemer has written: 'Mechanisms of immunological self-tolerance' -- subject(s): Immunology, T-Lymphocytes, Autoimmunity, Immunological tolerance, B-Lymphocytes, Immune Tolerance
Discoid lupus is not contracted because it is not caused by a pathogen (virus, bacteria, or parasite). Discoid develops in people who are genetically predisposed to autoimmunity and in the presence of triggers, most notably ultra violet light.
Bouts of pnuemonia do not cause autoimmune disease. However, some individuals with certain autoimmune diseases are more prone to pneumonia, and recurrent pneumonia itself may indicate a problem with the immune system, including autoimmunity.