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Gene therapy is a treatment of disease by replacing genes.

Recombinant DNA is a DNA resulting from gene-linking. That is when a DNA extracted from two or more different sources such as genes from different organisms and joined together to form a single molecule or fragment.

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9y ago
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12y ago

On the surface, there appears to be little if any similarity. In the broadest of definitions, gene therapy is the insertion of genetic material into a cells genome to produce a desired effect. In the process of making a transgenic organism, this is exactly is what is done to an embryo or gamete. In this sense, transgenic organisms are produced using a technique that is also used in gene therapy, but with very different mechanisms, and for very different reasons.

Transgenic organism is specifically this: an organism grown from an embryo that has been modified with genetic material from another organism in an attempt to improve some function or structure of the organism. An example of this would be BT Corn with a higher resistance to pests.

Gene therapy is an attempt at replacing or repairing dysfunctional or detrimental genes in a fully formed organism. This must be carried out by a vector (something to carry and insert the modified DNA to the correct cells).

The most common vectors are viruses, whose envelope may be changed to carry engineered genetic material and bind to the desired target cells. This is one of the difficult parts of gene therapy, viruses are fairly simple, and getting large amounts of genetic material into them is a challenge. Once the vector with the engineered DNA is injected into the target organism, the virus binds to its target cell and inserts the DNA into its genome. This can have the effect of replacing or repairing faulty genes like those responsible for some kinds of blindness, muscular wasting diseases, certain kinds of Diabetes, and all sorts of diseases that are caused by slightly irregular DNA sequences that result in irregular protein shapes or receptor affinity/response. If a disease is caused by a faulty protein or receptor, gene therapy may be able to treat it. Gene therapy is having a lot of growing pains, but holds great potential to treat or cure many of the world's worst diseases.

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12y ago

Gene therapy is when doctors take a sample and instead of changing or killing a tumour using drugs, they actually alter the very genetic make-up using gene-splicing technology.

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Q: How does recombinant DNA compare with gene therapy?
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Compare and contrast the technologies of using recombinant DNA and gene therapy?

Gene therapy is a treatment of disease by replacing genes. Recombinant DNA is a DNA resulting from gene-linking. That is when a DNA extracted from two or more different sources such as genes from different organisms and joined together to form a single molecule or fragment.


Is insertion of the insulin gene in E. coli an example of gene therapy?

No, its a good example of genetic engeneering though. To be more specific, it is an example of recombinant DNA technology.


How does recombinant DNA help cure diseases like diabetes?

recombinant dna has a foriegn gene that contains the coded information for the preparation of proper gene which is then placed instead of mutated gene........     


What describes the process of DNA Recombinant?

There are steps you must follow in the making of recombinant DNA such as use crosses to identify donor, clone gene in bacterium, characterize the gene, modify the gene, and reintroduce the gene into donor cells.


What can replace a gene in an animal's genome?

Recombinant DNA can replace a gene in an animal's genome.


What is recombinant DNA and how is it formed?

when a part or code of the dna is cut and spliced elsewhere it is called recombinant dna. an example direct injection of new dna into the nucleus with a gene gun


What step is not essential in producing recombinant DNA?

The step is not essential in producing recombinant DNA is reading the sequence of nucleotides of the particular gene being altered. Cutting the gene from the others is an essential step.


What is recombinant sequence?

A recombinant sequence of DNA is a sequence of DNA that comes from more than one source. Examples of recombinant DNA are plasmids that are put into bacteria. The plasmid comes from the bacteria (or a bacteria at least) but a target gene has been added (say the lac operon gene that allows bacteria to thrive on lactose), this plasmid is now a recombinant DNA sequence.


A plasmid that contains a gene for human growth hormone is and example of what?

recombinant dna


What are the requirements for recombinant DNA technology?

gene of interest 2.molecular scissor 3.molecular carrier or vector 4.expression system .These are the requirments for recombinant DNA technology.


Why might retroviral vectors for gene therapy increase the patient's risk of developing cancer?

They might integrate recombinant DNA into the genome in ways that misregulate the expression of genes at or near the site of integration


What is the first step in inserting a new gene into a bacterium?

recombinant DNA