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Cardiac ischemia occurs as a result of insufficient blood flow to the coronary blood vessels.

This often occurs due the formation of plagues in the coronary arteries. These plagues narrow the interior of these blood flows resulting in less blood flow to the heart. Angina (or chest pain) sometimes occur as a symptom of cardiac ischemia.

The heart has the highest oxygen consumption per tissue mass when compared to other organs in the human body. Blood will flow to the heart during its diastole phase. The heart's vasomotor tone is often controlled by its endothelium where healthy endothelial cells will release nitric oxide to cause vasodilation to improve blood flow. However, endothelial cells which are damaged by plague cannot produce nitric oxide as efficiently so the presence of plagues will decrease vasodilation and this will hinder blood flow. Angina will occur when the oxygen supply does not meet the heart's demand.

Propanolol can be used to treat cardiac ischemia. It is a non-selective beta-blocker. It can limit the heart rate by limiting the release to catecolamines. The diastolic coronary perfusion time will hence increase and this is favorable for cardiac ischemia. It also decreases due excitability of the heart and hence reduces the myrocardial oxygen demand.

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Q: How does propanolol treat cardiac ischemia?
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Patient experiences severe ischemia what can happen to heart?

Ischemia is a medical term meaning insufficient oxygen ... usually caused by insufficient blood flow. If the ischemia is occurring in the heart it will probably cause some type of cardiac problem: anything from mild cardiac failure (not pumping all the blood that the body demands) to pain (angina) to death of some or all of the cardiac muscle (a heart attack).


What causes global ceregral ischemia?

Global cerebral ischemia (GCI) is a serious condition caused by ventricular fibrillation or cardiac asystole, which stops all blood flow to the brain.


What is ischemic heart tissue?

Ischemia occurs when there is not enough oxygenated blood reaching the cardiac muscle cells.


Can you have a heart attack by having not enough oxygen in the cardiac muscle?

Yes, ischemia leads to heart arrest.


When a heart artery is clogged and heart muscle dies the condition is called?

irreversible ischemia


Is inferolateral ischemia curable?

Ischemia of any type is reversible. If ischemia is prolonged, it can turn to injury or infarction (in the case of the heart) and cell death, at which time it is not reversible or curable. There are studies with stem cells ongoing to attempt to regrow cardiac cells in heart attack scars, however, so this may not be a permanent condition forever.


What does inferolateral ischemia mean?

The term usually refers to a lack of oxygen in the cells of the side of the left ventricle (which is inferior/below and lateral/on-the-side of a standard electrocardiogram test. The lack of oxygen on the cellular level (also referred to as ischemia) is usually due to disrupted circulation to the heart muscle (in this case the left ventricular cardiac muscle). This is often due to a clot in the cardiac arteries which supply heart tissue with oxygenated blood. In short 'inferolateral ischemia' is a heart attack in the left ventricle.


How does nifedipine treat cardiac ischemia?

Cardiac ischemia occurs when there is reduced blood flow to the coronary arteries This usually occurs due to the formation of a plaque in the coronary artery resulting in the interior of the artery become narrowing and hence reduced blood flow to the heart. The blood contains oxygen so the heart receives less oxygen. Angina or chest pain will occur as a symptom of myocardial ischemia. Coronary blood flow is determined by the heart's oxygen demand. Nitric oxide can be released from healthy endothelium cells to result in vasodilation and increased blood flow. However, endothelium cells which are damaged by plagues will release fewer nitric oxide. The presence of plagues in blood vessels hence results in less vasodilation in its area. Nifedipine is a dihydropyridine. It can treat cardiac ischemia by acting as a vasodilator through the inhibition L-type voltage-sensitive calcium channels of smooth muscles. More blood will hence flow to the heart and meet its oxygen demands. It doesn't slow down cardiac conduction so it has no anti-arrthymic action. Although nifedipine has a negative inotropic effect, it is overshadowed by a reflex increase in heart rate and decreased afterload so it can ultimately improve blood flow to the heart.


Describe atherectomy to treat ischemia?

Atherectomy, in which the surgeon shaves off and removes strips of plaque from the blocked artery.


Describe laser angioplasty to treat ischemia?

Laser angioplasty, in which a catheter with a laser tip is inserted to burn or break down the plaque.


What impulses does a cardiac pacemaker use?

A cardiac pacemaker uses electric impulses to regulate a beating heart. Cardiac pacemakers are designed to treat various forms of arrhythmia (heart beat irregularities).


What is the term for decreased blood flow?

Ischemia is the medical term for decreased blood flow. Ischemia limits the supply of oxygen to tissues.