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Host specificity of a virus can be attributed to a few different factors. One of these factors is a viral species ability to "hijack" a cells internal machinery and cause it to reproduce the genetic makeup and proteins which make it up. Many viruses then exit the cell (usually through destroying it) and may take a part of the cell's membrane with them as a sort of phospholipid coat. This membrane has all of the identifying proteins which enable our cells to recognize one another and serves viruses in the same manner.

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Q: Host specificity of a virus is due to?
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What is most important for attachment of a virus to a host cell?

While we are constantly referring to bi-lateral specificity, as in the functions of Dna, here is a case where a virus offers out it's 'hand': it seems likely that it expects to reach for, find and attach to some outstretched Cell Membrane Component.


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