Cjonb and I have spent the last two days researching this. The results are as follows:This mixture may cause seizures...What apparently happened was that this problem was not noted in clinical trials of the drug, but was later reported in the field after the drug was approved. And so the labels were changed.A little background is necessary:* Tramadol itself can cause seizures, especially if the patient is overdosing* Trycyclic antidepressants are pretty extreme, as they have some nasty side effects. They're not quite the drug of last resort, but they're getting there.* If someone on tricyclics and tramadol seizes, it's very hard to identify the exact process that caused the seizure -- maybe the tramadol; maybe the psyche med; whoknows?* The Cyclobenzaprine molecule, like quite a few other compounds, has three rings in attached to a central structure, as do tricyclics. This alone would usually not be enough to counterindicate -- but in this oddball case, it is, or should have been.* These two meds were often prescribed together, and even today, probably still are.* The seizure risk, while extant, is not extreme.* Taking any drug means you're accepting a desired effect, and a few undesired ones. It's pretty much never purely all benefit. Tramadol is like this.
Yes. I'm taking both right now to sleep and it works awesome!
Unless you want serotonin syndrome no you should cconsult your doctor
Yeah it creates serotonin syndrome
Can you take Omeprazole and Cyclobenzaprine together? Thank you Pam
cyclobenzaprine and metonidazole taken together
Can you take cyclobenzaprine and cipro together
i all ready had taking cyclobenzaprine today can can i still take a benadryl
I wouldn't. I have no history of seizures and within a week of starting a cyclobenzaprine treatment, and had a seizure.
Can I take benzonatate and trazodone together
Absolutely not! That is a severe drug interaction.
Yes. In fact my doctor gave those two together.
I would not suggest taking two sedatives together.
no you will probably die. Mixing TOO many sleepers is deadly.
I have been prescribed them together along with seroquel......
Yes, if both are prescribed for you, there is no problem in taking those 2 drugs together. To get the "sleeping" effect of trazodone, without interfering with prozac antidepressant effect, the trazodone dosage should be around 25mg to 100mg.